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The drug significantly reduced the chronic inflammatory response and oxidative stress ( Novel dual- Glucagon-like peptide 1/glucose-dependent insulinotropic peptide receptor agonists are protective in animal models of Alzheimers disease The dual-receptor agonist DA3-CH that does not have any modifications, such as acylation to increase the survival time in the blood, enters the brain easier and shows good neuroprotective effects in the APP/PS1 mouse model

PMID: 19 Committee ADAPP

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Yao Z, Jiang X, Yao H, Wu Y, Zhang F, Wang C, et al